Hepatology Free

FIB-4 Index

Non-invasive liver fibrosis assessment.

Enter Values

Age (years)

Range: 18 - 120

AST (U/L)

Range: 1 - 5000

ALT (U/L)

Range: 1 - 5000

Platelet Count (10^9/L)

Range: 1 - 1000

Score

Author Richard K. Sterling et al.

First Published 2006

Evidence Guideline-endorsed (AASLD, EASL)

Category Hepatology

Original Study Development of a simple noninvasive index to predict significant fibrosis (Hepatology, 2006)

About FIB-4 uses age, AST, ALT, and platelet count to non-invasively assess likelihood of advanced liver fibrosis.

Clinical Use Initial triage of NAFLD or chronic hepatitis. Less reliable in patients <35 or >65 years.